CITRULLINE MALATE - 6G
Citrulline is a naturally occurring amino acid in the human body and can be found in foods such as watermelon. Citrulline is more effective at increasing nitric oxide levels than arginine for a variety of reasons. Citrulline doesn't break down in the liver and intestinal tract by arginase, unlike arginine. Citrulline bybasses the liver which makes it more favorable than arginine supplementation. A study done in 2018 shows citrulline can increase vasodilation, which is the widening of arteries or veins. It's associated with increased blood flow and lower blood pressure. After citrulline is ingested its converted into Arginine. Arginine is then converted into nitric oxide production with help from the enzyme nitric oxide synthase, which is the "pump" you experience during workouts. Citrulline has also been shown to increase protein synthesis by a crucial signaling pathway in muscle building. Citrulline Malate can improve weight training performance as well. A study done in 2015 showed participants were able to perform 52.92% more repetitions compared to the placebo group. Another Study in 2015 showed that it can increase endurance exercise. In this study, cyclists supplementing citrulline were able to cycle for 12% longer compared to the placebo group.
BETA-ALANINE - 3.2G
Beta-Alanine is a naturally occurring amino acid in the human body and can be found in foods such as meat and poultry. This ingredient may promote strength gain, lean body mass, and increased muscular endurance. The International Society of Sports Nutrition conducted an in depth study in 2015 using various methods of athletic training. This study showed that daily supplementation with 4-6 grams of beta-alanine per day for at least two to four weeks improved exercise performance and slowed neuromuscular fatigue. Another study done in 2018 showed that young adults were supplemented with 2.4g of beta alanine a day for 28 days. After 28 days the study showed beta alanine supplementation increased exercise capacity. Beta alanine supplementation has been shown to be most beneficial when exercising within one to four minutes, with a duration of sixty seconds or less being insignificant. If you are doing high intensity interval training, forced sets, super sets, drops sets, or sets lasting within the 1-4 minute time frame; this supplement will be most beneficial.
NITROSIGINE™ - 1.5G
Nitrosigine is a compound created by Nutrition 21 which is a complex of bonded silicon and arginine. This ingredient is quickly absorbed into the body, working within 15 minutes of consumption, providing you with increased blood flow, energy, and focus. A study done in 2016 gave two groups of healthy males 1.5 grams of Nitrosigine for fourteen and thirteen days. The study showed that with a single dose, Nitrosigine increases focus and mental acuity by 33% within 15 minutes. A second in vitro study was done to test potency of 1.5 grams of Nitrosigine against 1.5 grams of L-Arginine, 4 grams of L-Arginine AKG. 3 grams of L-Citrulline / Citrulline Malate and 1 gram of Agmatine Sulfate. The study showed there was a 5x greater increase in nitric oxide production with Nitrosigine than any of these ingredients.
VASO6™ - 300MG
VASO6 is a green tea oligomer created by Compound Solutions. Green tea extract increases bioavailability and amount of nitric oxide within the body. A 2014 Study showed green tea extract is capable of regulating eNOS and ROS production which increases the production of nitric oxide. Benefits of green tea extract include increased blood flow and lower blood pressure, all while lessening the strain on the heart and cardiovascular system.
BETAINE ANHYDROUS - 2.5G
Betaine Anhydrous is naturally occurring chemical in the human body and can be found in foods such as spinach, seafood, and whole grains. This ingredient has been found to have a positive impact on body composition and strength. A study done by the University of Connecticut showed that subjects given a dose of 1.25 grams for fourteen days had increased strength performance due to increased anabolic hormone levels (GH and IGF-1) and decreased catabolic hormone levels (cortisol).
KSM-66 - 500MG
KSM-66 is an ashwagandha extract made by Ixoreal Biomed that took fourteen years of research to develop. This ingredient has been examined in a whopping 22 clinical studies, all of which can be found here. Benefits have been shown to be decreased stress, enhanced memory and cognitive function, increased testosterone levels in men, enhanced muscle strength, size, and recovery. A study done in 2012 gave a test group 300mg of Ashwagandha for 60 days which groups resistance towards stress resistance improved, thus improving their mood.A study done in 2015 gave participants 300 mg of KSM-66 2x daily over a course of 8 weeks. The participants had increased muscle strength, muscle size and increased testosterone levels. In addition, they experienced significant decreases in muscle damage and reduction in body fat percentage. The effect for female sexual function was also done in a study in 2015 in which participants were given 300mg 2x daily for 8 weeks. After 8 weeks their Female Sexual Function Index (FSFI) score was improved, including sexual satisfaction.
BIOPERINE® - 5MG
BioPerine is an extract taken from black pepper fruits (piper longum) created by the Sabinsa Corporation. This ingredient increases the bioavailability of certain nutrients by at least 30%.
N-ACETYL L-TYROSINE - 250MG
N-Acetyl L-Tyrosine (NALT) is an acetylated form of L-Tyrosine, an amino acid that is naturally produced in the human body. This ingredient increases attention, alertness, focus, and improves memory retention and learning capability according to a 2017 clinical study. The brain converts L-Tyrosine to L-Dopa which produces dopamine. Dopamine is one of the brains neurotransmitters that contributes to positive feelings such as pleasures and satisfaction, hence the “feel good” effect. A typical dose in studies vary, but typically subjects were given 150mg per 1kg of weight. Our dose is 250mg due to the high concentrations of L-Tyrosine found in food sources from a typical diet. Examples of high L-Tyrosine foods can be found here.
CAFFEINE ANHYDROUS - 150MG
Caffeine anhydrous is dehydrated variant of regular caffeine. Due to the dehydration process, this form of caffeine is more concentrated and therefore more potent than regular caffeine. Caffeine anhydrous is 99% absorbed within 45 minutes after consumption. A study done in 2014 showed that after subjects ingested caffeine they completed significantly more exercise repetitions to failure and lifted heavier weight than those without caffeine supplementation. The same study also observed a greater mood state while decreasing perceived fatigue compared with the placebo group.
CAFFEINE CITRATE - 250MG (125MG OF ACTIVE CAFFEINE)
Caffeine citrate is a combination of caffeine anhydrous, citric acid monohydrate, and sodium citrate dihydrate. Caffeine citrate has many of the same benefits of natural caffeine; however, this is not a naturally occurring caffeine and requires a lab to synthesize. Caffeine citrate may peak blood levels 30 minutes to 2 hours after consumption, Caffeine citrate comes in a 2:1 ratio meaning it will yield half the amount of active caffeine than the amount ingested.
DICAFFEINE MALATE - 100MG (75MG OF ACTIVE CAFFEINE)
Dicaffeine malate is a bonded combination of approximately 75% caffeine and 25% malic acid. Believe it or not, after cocaine was banned from consumer products, Coca-Cola used dicaffeine malate as a stimulant replacement. The main difference in this form of caffeine is the malic acid, which may combat the digestive problems caused by caffeine anhydrous and natural caffeine. Some findings suggest that it lessens the post caffeine crash and helps replenish the energy produced by caffeine. There are no clinical studies to back this claim, so we have to rely on manufacturer claims and consumer reports and reviews.
L-THEANINE - 200MG
L-theanine is a non-essential amino acid that occurs naturally in green tea and black tea. This ingredient has been found to aid in sleep quality and improve mental focus. A study done in 2012 found that participants that took 100mg of L-theanine made fewer mistakes in an attention-oriented tasks. When combined with caffeine, the error rates during testing were significantly reduced. The conclusion from these findings is that L-theanine supplementation paired with caffeine may improve cognitive function. Another study in 2016 showed that 200mg of L-theanine provided a significant reduction in anxiety.
ALPHA-GPC - 500MG
Alpha GPC is naturally occurring compound found in the human body in small amounts. This ingredient is an up-and-coming and popular ergogenic supplement that is still undergoing studies. Studies have show that it may improve memory and enhance cognition, increase strength and post-workout recovery, and may act as a neuroprotectant. A study done in 2017 found that participants that took 250mg and 500mg of Alpha-GPC showed elevated serum free choline levels as opposed to placebo. Choline is an essential nutrient that you must get the majority of through diet. Alpha-GPC metabolizes into choline within the GI tract and the brain. Choline is a precursor to the neurotransmitter acetylcholine. Acetylcholine has been shown to help cognitive functions including concentration, focus, memory, and learning ability.